ribosomes
Ribosomes are large intracellular aggregates attached to the rough endoplasmic reticulum. They comprise several RNAs and scores of proteins, and function as ribozymes.
Ribosome biogenesis in eukaryotes mainly occurs in the nucleolus, a specialized nuclear compartment. The synthesis of ribosomal (rRNAs) is not achieved by simple transcription of the individual rRNA species, rather it requires a complex series of post-transcriptional processing steps.
Largest Computational Biology Simulation Mimics Life's Most Essential Nanomachine: "The ribosome is so fundamental to life that many portions of this molecular machine are identical in every organism ever genetically sequenced. In developing the project, the team identified a corridor inside the ribosome that the transfer RNA must pass through for the decoding to occur, and it appears to be constructed almost entirely of universal bases, implying that it is evolutionarily ancient." The original news release can be found here. Voxel simulation image : Image 2 : Image 3 : Image 4 : Image 5 : High res movie : Low res movie : See an image of the Q machine at http://www.lanl.gov/asci/.
Ribosome biogenesis in eukaryotes mainly occurs in the nucleolus, a specialized nuclear compartment. The synthesis of ribosomal (rRNAs) is not achieved by simple transcription of the individual rRNA species, rather it requires a complex series of post-transcriptional processing steps.
Largest Computational Biology Simulation Mimics Life's Most Essential Nanomachine: "The ribosome is so fundamental to life that many portions of this molecular machine are identical in every organism ever genetically sequenced. In developing the project, the team identified a corridor inside the ribosome that the transfer RNA must pass through for the decoding to occur, and it appears to be constructed almost entirely of universal bases, implying that it is evolutionarily ancient." The original news release can be found here. Voxel simulation image : Image 2 : Image 3 : Image 4 : Image 5 : High res movie : Low res movie : See an image of the Q machine at http://www.lanl.gov/asci/.
