Molecular Biology

Molecular Genetics

Researchers Discover How A High-fat Diet Causes Type 2 Diabetes

Researchers Discover How A High-fat Diet Causes Type 2 Diabetes: "In an article published in the December 29, 2005, issue of the journal Cell, the researchers report that knocking out a single gene encoding the enzyme GnT-4a glycosyltransferase (GnT-4a ) disrupts insulin production. Importantly, the scientists showed that a high-fat diet suppresses the activity of GnT-4a and leads to type 2 diabetes due to failure of the pancreatic beta cells. "

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